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Peptides and Non Peptides of Oncologic and Neuroendocrine Relevance From Basic to Clinical Research

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Peptides and Non Peptides of Oncologic and Neuroendocrine Relevance From Basic to Clinical Research

Peptides and Non Peptides of Oncologic and Neuroendocrine Relevance: From Basic to Clinical Research By A. V. Schally (auth.), Eugenio E. Müller (eds.)
2003 | 197 Pages | ISBN: 8847021707 | PDF | 9 MB



The book describes the ability of a series of endocrine-derived compounds, i.e. CHRH, LHRH, somatostatin, anti-androgens, and aromatase inhibitors to exert a direct anti-neoplastic activity or to potentiate the activity of traditional chemotherapeutic agents on neuroendocrine and solid tumors. In addition, a new class of potent GH-releasers, GSHs/Ghrelin, endowed with important endocrine and extra-endcocrine action, is presented. Therefore, in addition to traditional chemotherapy, characterized by high toxicity and non-selective action on tumoral cells, the reader can find a new approach with more selective, less cytotoxic endocrine derived compounds
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